Scientists have discovered that a new synthetic molecule named “DARP E2-79” could pave the way for quick-acting
remedies for a number of acute allergic reactions.
What is Allergy?
Allergy is a hypersensitivity
disorder of immune system. These reactions occur when a person’s immune
system reacts to normally harmless substances in the environment. The
substance which incites such a reaction is called an allergen. These reactions are acquired,
predictable, and rapid. When exposed to the allergen, the immune system
produces a type of antibody (IgE). IgE incites certain cells in our body (mast
cells and basophils) to produce chemical called histamine. Histamine is what is
responsible for the symptoms of your allergy.
How can “DARP E2-79” help?
In order to trigger an allergic
response, antiboby IgE needs to bind with a specific receptor called FcR. FcR
is a protein found on the surface of certain cells including mast cells, immune
cells present in the nasal lining and in the eyelids, along with IgE. Here
works DARP E2-79, whichdetaches IgE from its partner
FcR, thereby turning the process off.
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